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Image Search Results
Journal: Scientific reports
Article Title: Untargeted metabolomic profiling for identifying systemic signatures of helicobacter pylori infection in a guinea pig model.
doi: 10.1038/s41598-025-98016-w
Figure Lengend Snippet: Fig. 4. Classical univariate receiver operating characteristic curves generated from the spectral data to identify serum metabolomic biomarkers indicating H. pylori infection. Box plots representing the distribution of the normalized signal intensities come from: (a) 20-dihydroxyleukotriene B4 (HMDB0012635); (b) PGD2 ethanolamide (HMDB0013629); (c) L.L-Cyclo(leucylprolyl) (HMDB0034276); (d) LysoPC(P-16:0/0:0) (HMDB0010407); (e) PS(18:2(9Z.12Z)/18:2(9Z.12Z)) (HMDB0012402); (f) PG(18:2(9Z.12Z)/22:4(7Z. 10Z.13Z.16Z)) (HMDB0010656); (g) N-Lactoylleucine (HMDB0062176); (h) Isoleucyl-Phenylalanine (HMDB0028914); (i) 5-Methoxytryptophol (HMDB0001896); (j) Deoxycholic acid 3-glucuronide (HMDB0002596);) (k) PC(16:1(9Z)/14:1(9Z)) (HMDB0007999); (l) gamma-Aminobutyric acid (HMDB0000112). The boxes represent the interquartile range (difference between the upper 75% and lower quartile 25%), the thick black lines, and the median. A horizontal line is in red, indicating the optimal cutoff. Abbreviations: 0—H. pylori-negative; 1 – H. pylori positive.
Article Snippet: In serum samples from patients infected with influenza virus Banoei et al., using 1H-NMR, detected citrate; fumarate; 3-Methyl,2-Isovalerate; alanine; tyrosine; methionine; histidine; 4-hydroxybutyrate44, while in patients infected with COVID-19 LC–MS analysis showed the presence of bile acids, bilirubin, diacylglycerols, free fatty acid, glucose, glucuronate, glycerol 3-phosphate, kynurenine, lysophosphotidylcholines, malic acid, monosialodihexosylganglioside, phosphatidylcholines, sphingomyelin, Lp log2(FC) FC m/z RT (min) p-Value Name (ID in HMDB) Cellular locations Biological process 1 1.2063 2.31 368.2231 2.4 0.015061
Techniques: Generated, Infection